For many people with epilepsy, medication successfully controls seizures. But for others, seizures continue despite trying multiple treatments.
When seizures persist after two appropriate anti-seizure medications, this is called drug-resistant epilepsy. It affects nearly one in three people living with epilepsy.
If you are still experiencing seizures in Miami despite treatment, you are not alone — and you are not out of options.
When Seizures Continue Despite Medication
Ongoing seizures affect more than physical health. They can impact driving privileges, employment, independence, relationships, and emotional well-being.
Persistent seizures do not always mean medications ‘don’t work.’ Sometimes the seizure type needs to be reclassified. Sometimes updated brain imaging or prolonged EEG monitoring is necessary. In other cases, the underlying cause of seizures has not been fully identified.
After two medications fail, medical guidelines recommend referral for a comprehensive epilepsy evaluation — not simply increasing the dose or adding another prescription.
Comprehensive Epilepsy Evaluation in Miami
A thorough reassessment may include prolonged EEG monitoring, updated MRI imaging with an epilepsy protocol, and a detailed review of seizure patterns and medication response.
Dr. Andrew Lerman is a board-certified epileptologist providing advanced epilepsy care in Miami. As a specialist in seizure disorders, he performs comprehensive evaluations to determine why seizures remain uncontrolled and what next steps may be appropriate.
For some patients, advanced therapies such as epilepsy surgery, vagus nerve stimulation (VNS), or responsive neurostimulation (RNS) may significantly improve seizure control.
Access to Epilepsy Clinical Trials in Miami
Another important option for patients with uncontrolled seizures is participation in clinical trials. New medications are actively being developed specifically for refractory epilepsy — designed for patients whose seizures have not responded to standard therapies.
At Grove Neurology, we participate in several clinical trials for drug-resistant epilepsy. After a thorough neurologic evaluation, Dr. Lerman determines whether a patient may qualify.
Clinical trial participation is voluntary, carefully monitored, and conducted under strict safety guidelines. For eligible patients, it may provide access to innovative treatments before they become widely available.
When to Seek Emergency Care
A seizure lasting longer than five minutes, repeated seizures without full recovery, breathing difficulty, or serious injury requires immediate emergency medical attention.
Schedule an Epilepsy Evaluation in Miami
If you are still experiencing seizures despite treatment, it may be time for a comprehensive epilepsy evaluation.
Grove Neurology provides advanced epilepsy care in Miami, including diagnostic testing, treatment optimization, device evaluation, and access to clinical research.
Contact our office to schedule an appointment and explore your options for better seizure control.

